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Anti-Human CD5 DyLight® 488 conjugated Antibody

Boster Bio Anti-Human CD5 DyLight® 488 conjugated Antibody catalog # A00480-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Background

CD5 is a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. In humans, the gene is located on the long arm of chromosome 11. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

T-cell surface glycoprotein CD5; Lymphocyte antigen T1/Leu-1; CD5; CD5; LEU1

Gene Name

CD5 molecule

UniProt

P06127

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human CD5, which shares 92.1% and 89.5% amino acid (aa) sequence identity with mouse and rat CD5, respectively.

Clonality

Polyclonal

Conjugation

DyLight®488

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells, T Cells, T Lymphocytic Lineage

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

May act as a receptor in regulating T-cell proliferation.

Storage Conditions

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00480-Dyl488

Product MSDS

https://www.bosterbio.com/msds?sku=A00480-Dyl488

Fragment

Rabbit IgG

Applications Notes

6

Other Gene Names

CD5

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

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