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Anti-CDC25C Antibody (Monoclonal, DCS-193)

Boster Bio Anti-CDC25C Antibody (Monoclonal, DCS-193) catalog # MA1018. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Background

Cell division sycle (CDC25) gene product is a protein-tyrosine phosphatase, activates a partially purified p34 (cdc2) /cyclin B complex. The cdc25 protein also shares homology with a protein phosphatase with activity against both tyrosine and serine (and thus probably threonine) phosphate residues. CDC25C is expressed predominantly in G2 phase in healer cells. The human gene encodes a protein with a predicted molecular mass of 53,000 daltons whose C-terminal domain shares about 37% sequence identity with the fission yeast cdc25 mitotic inducer. CDC25C gene is mapped to 5q31.

Synonyms

Protein Cdc25c ; Cdc25c

Gene Name

Cell division cycle 25 homolog C (S. pombe)

UniProt

D4ADT2

Host

Mouse

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

Recombinant human Cdc25c.

Clonality

Monoclonal

Clone

Clone: DCS-193

Applications

WB

Field of Research

Cell Biology, Cell Cycle, Epigenetics and Nuclear Signaling, Kinases/Phosphatases

Purification

Ascites

Concentration

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Form

Lyophilized

Reconstitution

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Function

CDC25C: Functions as a dosage-dependent inducer in mitoticcontrol. Tyrosine protein phosphatase required for progression ofthe cell cycle. When phosphorylated, highly effective inactivating G2 cells into prophase. ly dephosphorylates CDK1and activates its kinase activity.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=MA1018

Product MSDS

https://www.bosterbio.com/msds?sku=MA1018

Fragment

Mouse IgG1

Applications Notes

Western blot, 1-2μg/ml, Human<br>

Other Gene Names

CDC25C

Subcellular Location

CDC25C: Nucleus |Cdc25c: Nucleus.

Sequence Similarities

Belongs to the MPI phosphatase family.

Protein Name

M-phase inducer phosphatase 3

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