Anti-Cathepsin D Ctsd Monoclonal Antibody

Boster Bio Anti-Cathepsin D Ctsd Monoclonal Antibody catalog # MA1013. Tested in IHC, WB applications. This antibody reacts with Human.

Product Specifications

Background

Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Cathepsin D is mapped to chromosome 11. The amino acid sequence predicted from the cDNA sequence shows that human cathepsin D consists of 412 amino acids with 20 and 44 amino acids in a pre- and a prosegment, respectively.

Synonyms

Cathepsin D;3.4.23.5; Cathepsin D 12 kDa light chain; Cathepsin D 9 kDa light chain; Cathepsin D 34 kDa heavy chain; Cathepsin D 30 kDa heavy chain; Ctsd

Gene Name

Cathepsin D

UniProt

P24268

Host

Mouse

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

Human liver cathepsin D.

Clonality

Monoclonal

Clone

Clone: CTD-19

Tissue Specificity

CTSD: Expressed in the aorta extrcellular space (atprotein level) .

Applications

IHC, WB

Field of Research

Cancer, Cell Adhesion Proteins, Cell Biology, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Membrane Proteins, Neuroscience, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction

Purification

Ascites

Concentration

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Form

Lyophilized

Reconstitution

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Function

Acid protease active in intracellular protein breakdown.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=MA1013

Product MSDS

https://www.bosterbio.com/msds?sku=MA1013

Fragment

Mouse IgG2a

Applications Notes

Immunohistochemistry (Paraffin-embedded Section), 1-2μg/ml, Human, By Heat <br>Western blot, 0.5-1μg/ml, Human<br>

Other Gene Names

CTSD

Subcellular Location

Lysosome. Melanosome . Secreted, extracellular space .

Sequence Similarities

Belongs to the peptidase A1 family.

Protein Name