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Mouse FABP2 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Mouse FABP2 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development) . Quantitate Mouse Fabp2 in cell culture supernatants, serum and plasma (heparin, EDTA) .

Product Specifications

Background

Fatty acid-binding protein 2 (FABP2), also known as Intestinal-type fatty acid-binding protein (I-FABP) is a protein that in humans is encoded by the FABP2 gene. The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. Using a human cDNA probe for in situ hybridization studies, they regionalized the assignment to 4q28-q31. The intestinal form of FABP was mapped to mouse chromosome 3 between the amylase and alcohol dehydrogenase-3 loci. Also, they may be responsible in the modulation of cell growth and proliferation.

Synonyms

Fatty acid-binding protein, intestinal; Fatty acid-binding protein 2; Intestinal-type fatty acid-binding protein; I-FABP; Fabp2; Fabpi

Gene Name

Fatty acid binding protein 2, intestinal

UniProt

P55050

Reactivity

Mouse

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: E.coli; Immunogen sequence: A2-E132

Tissue Specificity

Expressed in the small intestine. Highest expression levels in the proximal ileum.

Applications

ELISA

Sample Type

Cell culture supernatants, serum and plasma (heparin, EDTA) .

Detection Range

31.2 pg/ml - 2,000 pg/ml

Function

FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.

Storage Conditions

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EZ1622

Product MSDS

https://www.bosterbio.com/msds?sku=EZ1622

Other Gene Names

Fabp2

Subcellular Location

Cytoplasm.

Curated Selection

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