P38 MAPK-IN-4
P38 MAPK-IN-4 (compound 6) is a p38 MAPK inhibitor with an IC50 of 35 nM[1].
Product Specifications
CAS Number
[219138-24-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
P38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/p38-mapk-in-4.html
Purity
98.69
Solubility
DMSO : 20 mg/mL (ultrasonic; adjust pH to 2 with 1M HCl)
Smiles
O=C1N(C2=CC=C(Cl)C=C2)NC(C3=CC=NC=C3)=C1C4=CC=C(F)C=C4
Molecular Formula
C20H13ClFN3O
Molecular Weight
365.79
Precautions
H302, H315, H319
References & Citations
[1]S E de Laszlo, et al. Pyrroles and other heterocycles as inhibitors of p38 kinase. Bioorg Med Chem Lett. 1998 Oct 6;8 (19) :2689-94.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P38 MAPK
Available Sizes
Curated Selection
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