EB1002

EB1002 is a selective NK2R agonist. EB1002 significantly raises the expression levels of mitochondrial biosynthesis-related genes (like PGC-1α) in obese mice, indicating that it promotes energy expenditure by boosting mitochondrial activity. EB1002 also increases the insulin sensitivity and improves glycolipid metabolism of the mice. EB1002 is promising for research of obesity and type 2 diabetes[1].

Product Specifications

CAS Number

[2770688-48-5]

UNSPSC

12352209

Target

Neurokinin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/eb1002.html

Purity

99.98

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 48.78 mg/mL (adjust pH to 3 with 1 M HCl)

Smiles

O=C(CCCCCCCCCCCCCCCCC(O)=O)N[C@H](C(O)=O)CCC(NCCOCCOCC(NCCOCCOCC(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](C(C)C)C(NCC(N(C)[C@@H](CC(C)C)C(N[C@@H](CCOC)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O