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BB-Cl-Yne

Product Specifications

UNSPSC Description

BB-Cl-Yne is a protein arginine deiminase (PAD) inhibitor with Ki values of PAD1-4.are 6400, 3600, 10800, 4900 M-1min-1 respectively. BB-Cl-Yne can be used as a click probe to label PAD[1].

Target Antigen

Protein Arginine Deiminase

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bb-cl-yne.html

Smiles

O=C(C1=CC=C(C2=CC=C(C#C)C=C2)C=C1)N[C@H](C3=NC4=CC=CC=C4N3)CCCNC(CCl)=N

Molecular Weight

483.99

References & Citations

[1]Nemmara VV, et al. The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs). ACS Chem Biol. 2018 Mar 16;13(3):712-722.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-137125/BB-Cl-Yne-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-137125/

Clinical Information

No Development Reported

CAS Number

2219324-71-5

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