ARN14686
Product Specifications
UNSPSC Description
ARN14686 is an activity-based protein profiling (ABPP) probe. ARN14686 inhibits hNAAA with high potency (IC50=0.006 μM). ARN14686 interacts with NAAA via covalent binding to the N-terminal cysteine. ARN14686 binds only to the catalytically active form of NAAA, and may serve therefore as an efficient activity-based probe[1].
Target Antigen
Fluorescent Dye
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/arn14686.html
Smiles
O=C(OCCCCCCCCCC#C)N[C@H]1CNC1=O
Molecular Weight
280.36
References & Citations
[1]Romeo E, et al. Activity-Based Probe for N-Acylethanolamine Acid Amidase. ACS Chem Biol. 2015 Sep 18;10(9):2057-2064.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-125384/ARN14686-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-125384/
Clinical Information
No Development Reported
CAS Number
1628345-10-7
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