(1-Nitroethene-1,2-diyl)dibenzene
Product Specifications
UNSPSC Description
(1-Nitroethene-1,2-diyl)dibenzene (alpha-Nitrostilbene; α-Nitrostilbene) is an inhibitor of protein arginine methyltransferase 1 (PRMT1; IC50=11 μM in histone H4 methylation assay). It also inhibits histone H4 methylation by PRMT8, but not histone H3.1 methylation by CARM1 or Set7/9, at concentrations of 10 and 100 μM.
Target Antigen
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/1-nitroethene-1-2-diyl-dibenzene.html
Smiles
O=[N+](/C(C1=CC=CC=C1)=C/C2=CC=CC=C2)[O-]
Molecular Weight
225.24
References & Citations
[1]Dillon, et al. Novel inhibitors for PRMT1 discovered by high-throughput screening using activity-based fluorescence polarization. ACS Chem. Biol. 7(7), 1198-1204 (2012).
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W013500/1-Nitroethene-1-2-diyl-dibenzene-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W013500/
Clinical Information
No Development Reported
CAS Number
1215-07-2
Curated Selection
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