Ochnaflavone
Product Specifications
UNSPSC Description
Ochnaflavone is an inhibitor of IIA-type secretory phospholipase A2 (sPLA2-IIA) with an IC50 of 3.45 µM. Ochnaflavone exhibits significant anti-inflammatory and liver-protective effects, capable of inhibiting the degradation of phosphatidylethanolamine (PE) and lipid peroxidation induced by carbon tetrachloride (CCl4) in rat liver, with an IC50 of 7.16 µM for lipid peroxidation. Ochnaflavone can be used in research on liver damage and inflammatory diseases[1].
Target Antigen
Phospholipase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ochnaflavone.html
Smiles
O=C1C=C(C2=CC=C(OC3=CC(C4=CC(C5=C(O)C=C(O)C=C5O4)=O)=CC=C3O)C=C2)OC6=CC(O)=CC(O)=C16
Molecular Weight
538.46
References & Citations
[1]Moon TC, et al. Ochnaflavone, naturally occurring biflavonoid, inhibits phospholipase A2 dependent phosphatidylethanolamine degradation in a CCl4-induced rat liver microsome. Biol Pharm Bull. 2006 Dec;29(12):2359-61.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N7327/Ochnaflavone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N7327/
Clinical Information
No Development Reported
CAS Number
50276-96-5
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