His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 (TFA)
Product Specifications
UNSPSC Description
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels[1].
Target Antigen
Cholinesterase (ChE); Endogenous Metabolite
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease;Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/his-d-beta-nal-ala-trp-d-phe-lys-nh2-tfa.html
Purity
99.31
Solubility
10 mM in DMSO
Smiles
NCCCC[C@@H](C(N)=O)NC([C@@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](C)NC([C@H](NC([C@@H](N)CC2=CN=CN2)=O)CC3=CC4=C(C=CC=C4)C=C3)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O.OC(C(F)(F)F)=O
Molecular Weight
998.06
References & Citations
[1]Akman MS, et al. Mechanisms of action of a second generation growth hormone-releasing peptide (Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2) in rat anterior pituitary cells. Endocrinology. 1993 Mar;132(3):1286-91.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P5189A/His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P5189A/His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2-TFA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Curated Selection
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