L687
L687 is a potent activator of TRPC3/C6/C7 that can induce cellular uptake of oligonucleotides[1].
Product Specifications
CAS Number
[2776151-36-9]
UNSPSC
12352005
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/l687.html
Purity
99.49
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N1CCCCC1)C2=CC(Cl)=C(N3CCN(CC(NC4=C(OCC)C=CC=C4)=O)CC3)C=C2
Molecular Formula
C26H33ClN4O3
Molecular Weight
485.02
References & Citations
[1]Hiroto Kohashi, et al. A novel transient receptor potential C3/C6 selective activator induces the cellular uptake of antisense oligonucleotides. Nucleic Acids Res. 2024 May 22;52 (9) :4784-4798.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TRPC3; TRPC6; TRPC7
Available Sizes
Curated Selection
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