Rabbit PTK7 / CCK4 Protein, His Tag (MALS verified)

PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 66.4 kDa. The protein migrates as 100-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

G1SIJ6-1

Expression Region

Ala 31 - Thr 612

Host

HEK293

Target

PTK7

Conjugation

Unconjugated

Tag

C-10xHis

Source

Rabbit

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Bioactivity

Immobilized Rabbit PTK7, His Tag (Cat. No. PT7-R52H4) at 1 μg/mL (100 μL/well) can bind Cofetuzumab Pelidotin with a linear range of 0.2-4 ng/mL (Routinely tested).

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

66.4 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Storage Conditions

-20°C

Package Size

1mg*1

Host or Source

HEK293

Species

Rabbit

Protein ID

G1SIJ6-1

Preservative

Trehalose

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