Methoxyflurane

Methoxyflurane disrupts neuronal transmission by interfering with the release and re-uptake of neurotransmitters at post-synaptic terminals, or altering ionic conductance following receptor activation[1]. Methoxyflurane is an analgesic agent that provides rapid short-term analgesia. Methoxyflurane may shows a effective non-opioid treatment option for trauma pain[2].

Product Specifications

CAS Number

[76-38-0]

Product Name Alternative

DA-759

UNSPSC

12352211

Hazard Statement

H226-H319-H341

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/methoxyflurane.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

COC(F)(F)C(Cl)Cl

Molecular Formula

C3H4Cl2F2O

Molecular Weight

164.97

Precautions

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P405-P501

References & Citations

[1]Mercadante S, et al. Analgesic Efficacy, Practicality and Safety of Inhaled Methoxyflurane Versus Standard Analgesic Treatment for Acute Trauma Pain in the Emergency Setting: A Randomised, Open-Label, Active-Controlled, Multicentre Trial in Italy (MEDITA) .Adv Ther. 2019 Nov;36 (11) :3030-3046.|[2]NCI Drug Dictionary.methoxyflurane