ICI 169369
Product Specifications
UNSPSC Description
ICI 169369 is an orally active, specific serotonin and 5-HT2/5-HT1C receptor competitive antagonist. ICI 169369 exhibits Ki values of 1.79 x 10−8 and 1.58 x 10−6 M for 5-HT2 and 5-HT1, respectively[1][2].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ici-169369.html
Smiles
CN(C)CCSC1=NC2=CC=CC=C2C=C1C3=CC=CC=C3.Cl
Molecular Weight
344.90
References & Citations
[1]D S Millson, et al. The effects of a 5-HT2 receptor antagonist (ICI 169,369) on changes in waking EEG, pupillary responses and state of arousal in human volunteers. Br J Clin Pharmacol. 1991 Oct;32(4):447-54.|[2]T P Blackburn, et al. In vitro studies with ICI 169,369, a chemically novel 5-HT antagonist. Eur J Pharmacol. 1988 Jun 10;150(3):247-56.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106805/ICI-169369-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106805/
Clinical Information
No Development Reported
CAS Number
85273-96-7
Curated Selection
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