Pan-RAS-IN-4
Product Specifications
UNSPSC Description
Pan-RAS-IN-4 (compound 2) is a potent inhibitor of RAS, with the IC50 of KRAS G12D. Pan-RAS-IN-4 plays an important rile in cancer research[1].
Target Antigen
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein;MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pan-ras-in-4.html
Purity
98.53
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=CC(C=CC(F)=C2CC)=C2C(N3CC4=NC(OC[C@@]56N(CCC6)C[C@@H](C5)F)=NC(N7CC8=C9C(C(N(CC9)C)=O)=NN8CCC7)=C4CC3)=C1
Molecular Weight
698.80
References & Citations
[1]ZSH Xu, et al. Nitrogen-containing polycyclic compound, and pharmaceutical composition and use thereof. WO2024067575A1
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163595/Pan-RAS-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163595/Pan-RAS-IN-4-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
3024060-23-6
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