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Fluoroclebopride

Product Specifications

UNSPSC Description

Fluoroclebopride binds reversibly to dopamine receptors. 18F labeled fluoroclebopride has been used as a probe for studying D2/D3 receptor availability via PET in various monkey models[1][2].

Target Antigen

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fluoroclebopride.html

Purity

99.90

Solubility

DMSO : ≥ 125 mg/mL

Smiles

O=C(NC1CCN(CC2=CC=C(F)C=C2)CC1)C3=CC(Cl)=C(N)C=C3OC

Molecular Weight

391.87

References & Citations

[1]Nader MA, Czoty PW. PET imaging of dopamine D2 receptors in monkey models of cocaine abuse: genetic predisposition versus environmental modulation. Am J Psychiatry. 2005 Aug;162(8):1473-82. |[2]Czoty PW, et al. Effects of repeated treatment with the dopamine D2/D3 receptor partial agonist aripiprazole on striatal D2/D3 receptor availability in monkeys. Psychopharmacology (Berl). 2013 Sep 29:10.1007/s00213-013-3274-7.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-102089/Fluoroclebopride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-102089/Fluoroclebopride-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

154540-49-5

Available Sizes

Curated Selection

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