Fluoroclebopride
Product Specifications
UNSPSC Description
Fluoroclebopride binds reversibly to dopamine receptors. 18F labeled fluoroclebopride has been used as a probe for studying D2/D3 receptor availability via PET in various monkey models[1][2].
Target Antigen
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fluoroclebopride.html
Purity
99.90
Solubility
DMSO : ≥ 125 mg/mL
Smiles
O=C(NC1CCN(CC2=CC=C(F)C=C2)CC1)C3=CC(Cl)=C(N)C=C3OC
Molecular Weight
391.87
References & Citations
[1]Nader MA, Czoty PW. PET imaging of dopamine D2 receptors in monkey models of cocaine abuse: genetic predisposition versus environmental modulation. Am J Psychiatry. 2005 Aug;162(8):1473-82. |[2]Czoty PW, et al. Effects of repeated treatment with the dopamine D2/D3 receptor partial agonist aripiprazole on striatal D2/D3 receptor availability in monkeys. Psychopharmacology (Berl). 2013 Sep 29:10.1007/s00213-013-3274-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-102089/Fluoroclebopride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-102089/Fluoroclebopride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
154540-49-5
Available Sizes
Curated Selection
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