ILT6, Human (HEK293, His)

LILRA3/CD85e/ILT6 functions as a soluble receptor for class I MHC antigens, binding both classical and non-classical HLA class I molecules, albeit with lower affinities than LILRB1 or LILRB2. It engages with monocyte surfaces, effectively suppressing LPS-induced TNF-alpha production by monocytes. ILT6 Protein, Human (HEK293, His) is the recombinant human-derived ILT6 protein, expressed by HEK293 , with C-6*His labeled tag.

THVQAGPLPK PTLWAEPGSV ITQGSPVTLR CQGSLETQEY HLYREKKTAL WITRIPQELV KKGQFPILSI TWEHAGRYCC IYGSHTAGLS ESSDPLELVV TGAYSKPTLS ALPSPVVTSG GNVTIQCDSQ VAFDGFILCK EGEDEHPQCL NSHSHARGSS RAIFSVGPVS PSRRWSYRCY GYDSRAPYVW SLPSDLLGLL VPGVSKKPSL SVQPGPVVAP GEKLTFQCGS DAGYDRFVLY KEWGRDFLQR PGRQPQAGLS QANFTLGPVS RSYGGQYTCS GAYNLSSEWS APSDPLDILI TGQIRARPFL SVRPGPTVAS GENVTLLCQS QGGMHTFLLT KEGAADSPLR LKSKRQSHKY QAEFPMSPVT SAHAGTYRCY GSLSSNPYLL THPSDPLELV VSGAAETLSP PQNKSDSKAG E