LLO (91-99)

LLO (91-99) (Listeriolysin O (91-99) ) is an exotoxin and class I MHC-restricted T-cell epitope of listeriolysin (LLO) . LLO (91-99) is processed by antigen-presenting cells, binds to MHC class I molecules and is presented to the cell surface. LLO (91-99) induces CTL responses and effectively eliminates Listeria from infected cells. LLO (91-99) can be used in the research of Listeria infections (e.g., listeriosis) [1][2][3].

Product Specifications

CAS Number

[137856-41-8]

Product Name Alternative

Listeriolysin O (91-99)

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/llo-91-99.html

Purity

99.24

Solubility

H2O : 50 mg/mL (ultrasonic; warming) |DMSO : ≥ 100 mg/mL

Smiles

O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H]([C@@H](C)CC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)CN

Molecular Formula

C47H67N11O17

Molecular Weight

1058.10

References & Citations

[1]N K Verma, et al. Delivery of class I and class II MHC-restricted T-cell epitopes of listeriolysin of Listeria monocytogenes by attenuated Salmonella. Vaccine. 1995 Feb;13 (2) :142-50.|[2]Carrero JA, et al. Listeriolysin o is strongly immunogenic independently of its cytotoxic activity. PLoS One. 2012;7 (3) :e32310. |[3]Calderón-González R, et al. Cellular vaccines in listeriosis: role of the Listeria antigen GAPDH. Front Cell Infect Microbiol. 2014 Feb 21;4:22.