Neobritannilactone B
Neobritannilactone B, a sesquiterpene, can be isolated from the chloroform fraction of the I. britannica. Neobritannilactone B is cytotoxic. Other extracts of I. britannica are also Dihydrofolate reductase (DHFR) inhibitors, which inhibit Shigella dysenteriae type 1[1][2].
Product Specifications
CAS Number
[886990-00-7]
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/neobritannilactone-b.html
Solubility
10 mM in DMSO
Smiles
C=C1C(O[C@H]2/C=C(CC/C=C(C[C@@H]([C@@H]12)O)\C)\C)=O
Molecular Formula
C15H20O3
Molecular Weight
248.32
References & Citations
[1]Choo SJ, et al. Hypo-pigmenting effect of sesquiterpenes from Inula britannica in B16 melanoma cells. Arch Pharm Res. 2014 May;37 (5) :567-74. |[2]Jose S, et al. Phytochemical constituents of Inula britannica as potential inhibitors of dihydrofolate reductase: A strategic approach against shigellosis. J Biomol Struct Dyn. 2022;40 (22) :11932-11947.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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