VU0486321
Product Specifications
UNSPSC Description
VU0486321 is a compound in a class of mGlu1 positive allosteric modulators (PAMs). VU0486321 maintains acceptable mGlu1 PAM potency, DMPK profile, CNS permeability, and mGluR selectivity.
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu0486321.html
Smiles
FC1=C2C(C(N(C2=O)C3=CC=C(C=C3Cl)NC(C4=C(C=CO4)C)=O)=O)=CC=C1
Molecular Weight
398.77
References & Citations
[1]Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 3. Engineering plasma stability by discovery and optimization of isoindolinone analogs
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-118179/VU0486321-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-118179/
Clinical Information
No Development Reported
CAS Number
1816301-67-3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
