(±) -CPSI-1306
(±) -CPSI-1306 is an orally available antagonist of macrophage migration inhibitory factor (MIF) .
Product Specifications
CAS Number
[1309793-47-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Macrophage migration inhibitory factor (MIF)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/__plusmn__-CPSI-1306.html
Purity
99.64
Solubility
DMSO : 6 mg/mL (ultrasonic)
Smiles
FC1=C(C=CC(F)=C1)C2=NOC(CC(N3CCOCC3)=O)C2
Molecular Formula
C15H16F2N2O3
Molecular Weight
310.30
Precautions
H302, H315, H319, H335
References & Citations
[1]Sanchez-Zamora Y, et al. Macrophage migration inhibitory factor is a therapeutic target in treatment of non-insulin-dependent diabetes mellitus. FASEB J. 2010 Jul;24 (7) :2583-90.|[2]Nagarajan P, et al. MIF antagonist (CPSI-1306) protects against UVB-induced squamous cell carcinoma. Mol Cancer Res. 2014 Sep;12 (9) :1292-302.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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