(±) -CPSI-1306

(±) -CPSI-1306 is an orally available antagonist of macrophage migration inhibitory factor (MIF) .

Product Specifications

CAS Number

[1309793-47-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Macrophage migration inhibitory factor (MIF)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/__plusmn__-CPSI-1306.html

Purity

99.64

Solubility

DMSO : 6 mg/mL (ultrasonic)

Smiles

FC1=C(C=CC(F)=C1)C2=NOC(CC(N3CCOCC3)=O)C2

Molecular Formula

C15H16F2N2O3

Molecular Weight

310.30

Precautions

H302, H315, H319, H335

References & Citations

[1]Sanchez-Zamora Y, et al. Macrophage migration inhibitory factor is a therapeutic target in treatment of non-insulin-dependent diabetes mellitus. FASEB J. 2010 Jul;24 (7) :2583-90.|[2]Nagarajan P, et al. MIF antagonist (CPSI-1306) protects against UVB-induced squamous cell carcinoma. Mol Cancer Res. 2014 Sep;12 (9) :1292-302.