Aureonuclemycin

Aureonuclemycin can be isolated from Staphylococcus aureus to obtain its biosynthetic gene cluster. Aureonuclemycin exists in two forms: Type A and Type B. Aureonuclemycin A is a nucleoside antibiotic that is structurally similar to herbicides and contains adenine. Aureonuclemycin B contains 5′-deoxyadenosine and exhibits antibacterial activity. Aureonuclemycin can be used in the research of bacterial leaf blight in rice, citrus canker, and bacterial leaf spot in rice. [1][2].

Product Specifications

CAS Number

[123970-01-4]

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/aureonuclemycin.html

Solubility

10 mM in DMSO

Smiles

O[C@]12[C@@](O[C@@H]([C@H]([C@@H]2O)O)C(O)=O)([H])C[C@]3([H])[C@]([C@H]([C@H](N4C5=NC=NC(N)=C5N=C4)O3)O)([H])O1

Molecular Formula

C16H19N5O9

Molecular Weight

425.35

References & Citations

[1]Pan HX, et al. Elucidation of the Herbicidin Tailoring Pathway Offers Insights into Its Structural Diversity. Org Lett. 2019 Mar 1;21 (5) :1374-1378.|[2]Wang W, et al. Antibacterial Activity of Aureonuclemycin Produced by Streptomyces aureus Strain SPRI-371[J]. Molecules, 2022, 27 (15) : 5041.