Carnosic acid

Carnosic acid is an orally active lipid absorption inhibitor. Carnosic acid has demonstrated inhibition of oxidative stress and inflammation, suppression of cell proliferation, and antibacterial activity.

Product Specifications

CAS Number

[3650-09-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Bacterial

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Carnosic_acid.html

Purity

99.53

Solubility

DMSO : 130 mg/mL (ultrasonic)

Smiles

OC([C@@]([C@@]1([H])CCC2=CC(C(C)C)=C3O)(CCCC1(C)C)C2=C3O)=O

Molecular Formula

C20H28O4

Molecular Weight

332.43

Precautions

H302, H315, H319, H335

References & Citations

[1]Yesil-Celiktas O, et al. Inhibitory effects of rosemary extracts, carnosic acid and rosmarinic acid on the growth of various human cancer cell lines. Plant Foods Hum Nutr. 2010 Jun;65 (2) :158-63.|[2]Kiyofumi Ninomiya, et al. Carnosic acid, a new class of lipid absorption inhibitor from sage. Bioorg Med Chem Lett. 2004 Apr 19;14 (8) :1943-6.