2-Methylacetophenone

2-Methylacetophenone (O-Methylacetophenone) is a xanthine dehydrogenase (XDH) inhibitor. 2-Methylacetophenone competitively binds to the XDH active site, blocking the pathway for xanthine to be converted to uric acid. 2-Methylacetophenone can be used for the study of hyperuricemia[1].

Product Specifications

CAS Number

[577-16-2]

Product Name Alternative

O-Methylacetophenone

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Xanthine Oxidase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/2-methylacetophenone.html

Purity

99.90

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C1=CC=CC=C1C)=O

Molecular Formula

C9H10O

Molecular Weight

134.18

Precautions

H302, H315, H319, H335

References & Citations

[1]Chen M, et al. Potential candidates from a functional food Zanthoxyli Pericarpium (Sichuan pepper) for the management of hyperuricemia: high-through virtual screening, network pharmacology and dynamics simulations. Front Endocrinol (Lausanne) . 2024 Dec 11;15:1436360.