ER-851
ER-851 is a selective AXL inhibitor with oral activity with IC50 of 100 nM. ER-851 has antitumor activity[1].
Product Specifications
CAS Number
[2685738-33-2]
UNSPSC
12352005
Target
TAM Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/er-851.html
Smiles
O=C(C(C(N1C2=NC=C(C)C=C2)=O)=CN(C3CCCC3)C1=O)NC(C=C4F)=CC=C4OC5=NC=NC6=C5CCN(CC7CCN(C)CC7)C6
Molecular Formula
C36H41FN8O4
Molecular Weight
668.76
References & Citations
[1]Tsukamoto S, et al. ER-851, a Novel Selective Inhibitor of AXL, Overcomes Resistance to Antimitotic Drugs. Mol Cancer Ther. 2023 Jan 3;22 (1) :12-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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