8-Hydroxyamoxapine
8-Hydroxyamoxapine is an orally active antidepressant, which inhibits the reuptake of norepinephrine and serotonin at synapses[1].
Product Specifications
CAS Number
[61443-78-5]
Product Name Alternative
8-OHAMX
UNSPSC
12352005
Hazard Statement
H302
Target
GlyT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/8-hydroxyamoxapine.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C2OC3=CC=C(Cl)C=C3C(N4CCNCC4)=NC2=C1
Molecular Formula
C17H16ClN3O2
Molecular Weight
329.78
Precautions
P264-P270-P330-P501
References & Citations
[1]Calvo B, et al., Pharmacokinetics of amoxapine and its active metabolites. Int J Clin Pharmacol Ther Toxicol. 1985 Apr;23 (4) :180-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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