D-NMAPPD
D-NMAPPD ((1R,2R) -B13) is an acid ceramidase inhibitor. D-NMAPPD regulates NMDA receptor properties by enhancing endogenous production of ceramides. D-NMAPPD has anticancer effecs[1][2].
Product Specifications
CAS Number
[35922-06-6]
Product Name Alternative
(1R,2R) -B13
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d-nmappd.html
Purity
99.74
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
OC[C@H]([C@@H](C1=CC=C(C=C1)[N+]([O-])=O)O)NC(CCCCCCCCCCCCC)=O
Molecular Formula
C23H38N2O5
Molecular Weight
422.56
References & Citations
[1]Marie-Elaine Laurier-Laurin, et al.Blockade of lysosomal acid ceramidase induces GluN2B-dependent Tau phosphorylation in rat hippocampal slices. Neural Plast. 2014;2014:196812.|[2]M Selzner, et al.Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer. Cancer Res. 2001 Feb 1;61 (3) :1233-40.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
302448 200 µL
FGFR4 (Fibroblast Growth Factor Receptor 4, FGFR-4, Protein-Tyrosine Kinase Receptor MPK-11, CD334, Fgfr4, Fgfr-4, Mpk-11)
Ask
View Details 
