oxLig-1
Product Specifications
UNSPSC Description
oxLig-1 (7-Ketocholesteryl-9-carboxynonanoate) is the lipid moiety of oxidized low-density lipoprotein (oxLDL) and is a key ligand for β-glycoprotein I (β(2)-GPI). oxLig-1 causes nuclear translocation by activating the NF-κB pathway. oxLig-1 can be used in the study of atherosclerosis (AS)[1].
Target Antigen
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/oxlig-1.html
Smiles
O=C1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCCC(C)C)C)([H])[C@@]4(C(C[C@H](CC4)OC(CCCCCCCC(O)=O)=O)=C1)C
Molecular Weight
570.84
References & Citations
[1]Huang Z, et al. 7-ketocholesteryl-9-carboxynonanoate induced nuclear factor-kappa B activation in J774A.1 macrophages. Life Sci. 2010 Nov 20;87(19-22):651-7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-164813/oxLig-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-164813/
Clinical Information
No Development Reported
CAS Number
352523-18-3
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