5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol
Product Specifications
UNSPSC Description
5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol (Compound 3n) is an antimicrobial and antioxidant agent, that inhibits Escherichia coli and Staphylococcus epidermidis, with MIC of 8 and 4 μg/mL. 5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol exhibits antioxidant activity with IC50 of 17.47 μM using DPPH free radical-scavenging method[1].
Target Antigen
Bacterial; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5-pyridin-4-yl-1-3-4-oxadiazole-2-thiol.html
Solubility
10 mM in DMSO
Smiles
C1=C(C=CN=C1)C2=NN=C(O2)S
Molecular Weight
179.20
References & Citations
[1]Yarmohammadi E, et al., Ultrasound-assisted, low-solvent and acid/base-free synthesis of 5-substituted 1,3,4-oxadiazole-2-thiols as potent antimicrobial and antioxidant agents. Mol Divers. 2021 Nov;25(4):2367-2378.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W104752/5-Pyridin-4-yl-1-3-4-oxadiazole-2-thiol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W104752/
Clinical Information
No Development Reported
CAS Number
15264-63-8
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