Mianserin-d3

Mianserin-d3 is the deuterium labeled Mianserin (HY-B0188) . Mianserin is a Histamine 1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant[1].

Product Specifications

CAS Number

[81957-76-8]

Product Name Alternative

Mianserine-d3

UNSPSC

12352005

Hazard Statement

H225-H301+H311+H331-H370

Target

Histamine Receptor; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Solubility

10 mM in DMSO

Smiles

[2H]C([2H])([2H])N1CC2N(CC1)C3=CC=CC=C3CC4=CC=CC=C42

Molecular Formula

C18H17D3N2

Molecular Weight

267.38

Precautions

P210-P233-P240-P241-P242-P243-P260-P261-P264-P270-P271-P280-P302+P352-P303+P361+P353-P304+P340-P308+P311-P330-P361+P364-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Olianas MC, et al. The atypical antidepressant mianserin exhibits agonist activity at κ-opioid receptors. Br J Pharmacol. 2012 Nov;167 (6) :1329-41.|[2]Roeder T. High-affinity antagonists of the locust neuronal octopamine receptor. Eur J Pharmacol. 1990 Nov 27;191 (2) :221-4.