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Dinitolmide

Dinitolmide (Zoalene) is an orally active anticoccidial agent used as a fodder additive. Dinitolmide has a wide anticoccidial spectrum with no effect on host immunity. Dinitolmide mainly acts on the first generation merozoite stage of coccidia and also has an inhibitory effect on the sporulation process of oocysts. Dinitolmide has anti-Toxoplasma gondii effect in vitro with an EC50 of 3.625 μg/mL. Dinitolmide can be used to inhibits infections caused by Eimeria tenella[1][2].

Product Specifications

CAS Number

[148-01-6]

Product Name Alternative

Zoalene

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Dinitolmide.html

Concentration

10mM

Purity

99.66

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(N)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1C

Molecular Formula

C8H7N3O5

Molecular Weight

225.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Qu D, et al. Effect of dinitolmide intercalated into Montmorillonite on E. tenella infection in chickens. Parasitol Res. 2014 Mar;113 (3) :1233-8.|[2]Cao X, et al. In vitro anti-Toxoplasma gondii effects of a coccidiostat dinitolmide. Vet Parasitol. 2023 Apr;316:109903.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Coccidia; Toxoplasma

Available Sizes

Curated Selection

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