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FGF-23 Antibody / Fibroblast Growth Factor 23

Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

Product Specifications

UniProt

Q9GZV9

Host

Mouse

Immunogen

A recombinant fragment (within amino acids 100-251) of human FGF23 protein was used as the immunogen for the Fibroblast Growth Factor 23 antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Applications

IHC-P

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the Fibroblast Growth Factor 23 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Fibroblast Growth Factor 23 antibody is available for research use only.

CAS Number

9007-83-4

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