STMN1 Recombinant Antibody / Stathmin 1
Stathmin 1 (Oncoprotein 18, STM1, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of the protein are observed, and it is expressed as two different isoforms. Stathmin 1 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation. It is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.
Product Specifications
UniProt
P16949
Host
Mouse
Immunogen
A recombinant fragment (within amino acids 1-148) of human STMN1 protein was used as the immunogen for the recombinant STMN1 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Type
Recombinant
Applications
IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the recombinant STMN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant STMN1 antibody is available for research use only.
CAS Number
9000-83-3
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