Collagen IV Recombinant Antibody / COL4A3
Collagen Type IV is a major component of the basement membrane and plays an important role in cell adhesion, migration, differentiation and growth. Collagen Type IV express at the basement membranes in a variety of tissues including kidney, muscle, lymph nodes, lung, tendon and spleen. Collagen Type IV has been shown to be useful in differentiating microinvasive from in situ ductal carcinomas of the breast. Other Collagen Type IV studies include use in pancreatic adenocarcinoma and chronic pancreatitis, nephrosclerosis and other kidney diseases, oral squamous cell carcinoma, laryngeal cancers, ovarian cancers and cervical cancers.
Product Specifications
UniProt
P02462, P08572, P29400, P53420
Host
Rabbit
Immunogen
A recombinant fragment (within amino acids 1400-1670) of human COL4A protein was used as the immunogen for the Collagen IV antibody.
Clonality
Monoclonal
Isotype
IgG κ
Type
Recombinant
Applications
IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Collagen IV antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Collagen IV antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/51587083/datasheet/v5400-100ug.pdf
CAS Number
9000-83-3
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