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EGF Receptor / EGFR Recombinant Antibody

This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Product Specifications

UniProt

P00533

Host

Rabbit

Immunogen

A recombinant fragment (within amino acids 300-500) of human EGFR protein was used as the immunogen for the recombinant Epidermal growth factor receptor antibody.

Clonality

Monoclonal

Isotype

IgG κ

Type

Recombinant

Applications

IHC-P, WB

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the recombinant Epidermal growth factor receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This recombinant Epidermal growth factor receptor antibody is available for research use only.

Product Datasheet

https://cdn.gentaur.com/products/800/51587057/datasheet/v5391-20ug.pdf

CAS Number

9000-83-3

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