MARCHF2 Antibody / MARCH2 / Membrane-associated RING finger protein 2

MARCH2 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. MARCH2 may be involved in endosomal trafficking through interaction with STX6.

Product Specifications

UniProt

Q9P0N8

Host

Rabbit

Immunogen

An E.coli-derived human recombinant protein (M1-V246) was used as the immunogen for the MARCH2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IF, ELISA

Format

Antigen affinity purified

Buffer

0.5mg/ml if reconstituted with 0.2ml sterile DI water

Reconstitution

After reconstitution, the MARCH2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.