P4HTM Recombinant Antibody / HIFPH4 / HIF Prolyl Hydroxylases
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. [UniProt]
Product Specifications
UniProt
Q9NXG6
Host
Rabbit
Immunogen
A synthetic peptide derived from human HIF Prolyl Hydroxylases was used as the immunogen for the P4HTM antibody.
Clonality
Monoclonal
Isotype
IgG
Type
Recombinant
Applications
WB
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the P4HTM antibody at -20oC.
Limitations
This P4HTM antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/51577504/datasheet/rq8306.pdf
CAS Number
9000-83-3
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