N-Butyl lithocholic acid
Product Specifications
UNSPSC Description
N-Butyl lithocholic acid is a derivative of the secondary bile acid Lithocholic acid (HY-B0172).
Target Antigen
E3 Ligase Ligand-Linker Conjugates; Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/n-butyl-lithocholic-acid.html
Smiles
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(OCCCC)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])CC3)C
Molecular Weight
432.68
References & Citations
[1]Hou B, et al. Tumor-specific delivery of clickable inhibitor for PD-L1 degradation and mitigating resistance of radioimmunotherapy. Sci Adv. 2024 Nov 15;10(46):eadq3940.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-169393/N-Butyl-lithocholic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169393/
Clinical Information
No Development Reported
CAS Number
135013-42-2
Curated Selection
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