Apoptosis inducer 21

Apoptosis inducer 21 (Compound 5h) inhibits the proliferation of lung cancer cell H69AR with an IC50 of 1.58 μM. Apoptosis inducer 21 arrests the cell cycle at G0/G1 phase, induces apoptosis in H69AR[1].

Product Specifications

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/apoptosis-inducer-21.html

Smiles

CC1=C(O)C(CC(N2)=C(CC3=C(O)C(C(C4=CC=C(Br)C=C4)=O)=CC(C)=C3O)C5=C2C=CC=C5)=C(O)C(C(C6=CC=C(Br)C=C6)=O)=C1

Molecular Formula

C38H29Br2NO6

Molecular Weight

755.45

References & Citations

[1]Lin J, et al., Synthesis and biological evaluation of novel penindolone derivatives as potential antiproliferative agents against SCLC in vitro. Bioorg Med Chem Lett. 2024 Jul 2;110:129877.