Apoptosis inducer 21
Product Specifications
UNSPSC Description
Apoptosis inducer 21 (Compound 5h) inhibits the proliferation of lung cancer cell H69AR with an IC50 of 1.58 μM. Apoptosis inducer 21 arrests the cell cycle at G0/G1 phase, induces apoptosis in H69AR[1].
Target Antigen
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apoptosis-inducer-21.html
Smiles
CC1=C(O)C(CC(N2)=C(CC3=C(O)C(C(C4=CC=C(Br)C=C4)=O)=CC(C)=C3O)C5=C2C=CC=C5)=C(O)C(C(C6=CC=C(Br)C=C6)=O)=C1
Molecular Weight
755.45
References & Citations
[1]Lin J, et al., Synthesis and biological evaluation of novel penindolone derivatives as potential antiproliferative agents against SCLC in vitro. Bioorg Med Chem Lett. 2024 Jul 2;110:129877.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-159096/Apoptosis-inducer-21-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-159096/
Clinical Information
No Development Reported
Curated Selection
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