FDPS Antibody (Center Region)

Farnesyl diphosphate synthase is a key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:2000

UniProt

P14324

Host

Mouse

Reactivity

Human, Mouse

Immunogen

Recombinant human FDPS was used as the immunogen for the FDPS antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

1049CT13.1.4

Applications

Purity

Protein G purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the FDPS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This FDPS antibody is available for research use only.

Storage Conditions

Aliquot the FDPS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the FDPS antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of FDPS antibody at 1:2000: Lane 1) human HeLa, 2) (h) HepG2, 3) (h) U-251 MG and 4) mouse liver lysate. Predicted molecular weight ~48 kDa (isoform 1) and ~40 kDa (isoform 2) .