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Phospho-p95 NBS1 (Ser343) Recombinant Rabbit mAb

Product Specifications

Background

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

ATV; NBS; P95; NBS1; AT-V1; AT-V2

Swiss Prot

O60934

Reactivity

Human

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser343 of human p95 NBS1

Conjugation

Unconjugated

Applications

WB, ICC/IF, IP

Purity

Affinity Purification

Modification

Phosphorylated

Molecular Weight

95 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Host or Source

Rabbit

Available Sizes

Curated Selection

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