Phospho-Smad3 (Ser423/Ser425) Recombinant Rabbit mAb

Product Specifications

Background

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436

Swiss Prot

P84022

Reactivity

Human, Mouse

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser423/Ser425 of human Smad3

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF

Purity

Affinity Purification

Modification

Phosphorylated

Molecular Weight

52 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of Phospho-Smad3 (Ser423/425) in Jurkat, C6, CHO-K1, Hela cell lysates using Phospho-Smad3 (Ser423/425) antibody (1:1000 diluted) .