IKBKAP polyclonal antibody

Product Specifications

Background

The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

IKBKAP; DYS; ELP1; FD; IKAP; IKI3; TOT1

Swiss Prot

O95163

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human IKBKAP (NP_003631.2) .

Conjugation

Unconjugated

Applications

WB, IHC

Dilution

WB,1:1000 - 1:4000|IHC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .