CSNK1A1L polyclonal antibody
Product Specifications
Background
Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase Iα, Iγ, Iδ and Iε, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair, membrane trafficking, circadian rhythm, cell cycle progression, chromosome segregation, apoptosis and cellular differentiation. Casein kinase I isoform α-like (CSNK1A1L) is a 337 amino acid protein that shares a high degree of sequence similarity with the α isoform of casein kinase 1. CSNK1A1L resides in the cytoplasm and participates in the Wnt signaling pathway. By utilizing ATP within its protein kinase domain, CSNK1A1L phosphorylates a large number of proteins.
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Casein kinase I isoform alpha-like; CKI-alpha-like; CK1; CSNK1A1L
Swiss Prot
Q8N752
Reactivity
Human
Immunogen
Recombinant full length Human CSNK1A1L.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:500~1:2000 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 39 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CSNK1A1L polyclonal antibody detects endogenous levels of CSNK1A1L protein.
Applications Notes
Immunofluorescence analysis of HeLa cell using CSNK1A1L antibody. Blue: DAPI for nuclear staining.
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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