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C1QBP (K100) polyclonal antibody

Product Specifications

Background

C1q binding protein (C1QBP), also designated gC1q-R, p32 (p33) or HABP1 (hyaluronan-binding protein 1), is known to bind the globular heads of C1q molecules and inhibit C1 activation. C1QBP has been described as a complement receptor for C1q on B cells, neutrophils and mast cells. The C1QBP protein may form homodimers. C1QBP is expressed in vascular endothelial cells and has been found to be a multifunctional protein interacting with elements of complement, coagulation and kinin systems. In addition, C1QBP is a subunit of pre-mRNA splicing factor SF2/ASF.

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Complement component 1 Q subcomponent-binding protein, mitochondrial; ASF/SF2-associated protein p32; Glycoprotein gC1qBP; Short name=C1qBP; Hyaluronan-binding protein 1; Mitochondrial matrix protein p32; gC1q-R protein; p33; C1QBP; GC1QBP; HABP1; SF2P32

Swiss Prot

Q07021

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 80-130 of Human C1QBP.

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 32 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

C1QBP (K100) polyclonal antibody detects endogenous levels of C1QBP protein.

Applications Notes

Western blot (WB) analysis of C1QBP (K100) pAb at 1:2000 dilution Lane1:HEK293T whole cell lysate (5ug) Lane2:Jurkat whole cell lysate (5ug) Lane3:The Spleen tissue lysate of Mouse (20ug) Lane4:The Ovary tissue lysate of Rat (40ug)

Host or Source

Rabbit

CAS Number

9007-83-4

Available Sizes

Curated Selection

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