Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

HLA-G monoclonal antibody

Product Specifications

Background

HLA-G is a non-classical MHC molecule expressed by trophoblasts in placenta, thymic epithelial cells, and some tumors.Alternative splicing leads to generation of at least six isoforms, four that are transmembrane proteins and two that are soluble. It is an inhibitory molecule involved in immune tolerance and escape, originally studied for its role in maternal tolerance of the fetus during pregnancy. HLA-G binds ILT2, ILT4, and KIR2DL4, playing a role in the regulation of natural killer, T, and monocyte/macrophage cells . Its involvement in evasion of immune response makes it a potential target for immunotherapy.

CAS Number

9007-83-4

Structure Composition

Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Product Name Alternative

HLA-6.0; HLAG; HLA class I histocompatibility antigen, alpha chain G; HLA G antigen; MHC class I antigen G

Swiss Prot

P17693

Reactivity

Human

Immunogen

Recombinant fusion protein of human HLA-G. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

WB

Dilution

WB (1/500 - 1/1000)

Purity

This antibody is purified through a protein G column.

Modification

Unmodification

Molecular Weight

~ 43 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of HLA-G protein.

Applications Notes

Western blot analysis of HLA-G expression in A549 (A), Ramos (B), MDAMB231 (C) whole cell lysates.

Host or Source

Mouse

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Transcription factor E2F1 (aa480-493) (E2F1, E2F Transcription factor 1, E2F-1, RBAP1, RBBP3, RBP3, PBR3, PRB-binding protein E2F-1, RBAP-1, RBBP-3, Retinoblastoma-associated protein 1, Retinoblastoma-binding protein 3) (Drosophila)
208479 100 µg

Transcription factor E2F1 (aa480-493) (E2F1, E2F Transcription factor 1, E2F-1, RBAP1, RBBP3, RBP3, PBR3, PRB-binding protein E2F-1, RBAP-1, RBBP-3, Retinoblastoma-associated protein 1, Retinoblastoma-binding protein 3) (Drosophila)

Ask
View Details
NOL4L Antibody; FITC conjugated
MBS7006711-01 0.05 mg

NOL4L Antibody; FITC conjugated

Ask
View Details
NOL4L Antibody; FITC conjugated
MBS7006711-02 0.1 mg

NOL4L Antibody; FITC conjugated

Ask
View Details
NOL4L Antibody; FITC conjugated
MBS7006711-03 5x 0.1 mg

NOL4L Antibody; FITC conjugated

Ask
View Details
Mouse Monoclonal Occludin Antibody (OCLN/2181)
NBP3-07137-20ug 20 µg

Mouse Monoclonal Occludin Antibody (OCLN/2181)

Ask
View Details
Human LRRC33 (NRROS) (NM_198565) AAV Particle
RC208170A1V 250 µL

Human LRRC33 (NRROS) (NM_198565) AAV Particle

Ask
View Details