CRX Rabbit monoclonal antibody
Product Specifications
Background
Binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, e.g. NRL and RX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Cone rod homeobox; CORD 2; CRD; CRX; LCA7; OTX3
Swiss Prot
O43186
Reactivity
Human
Immunogen
A synthesized peptide derived from human CRX
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB 1:500~1:2000 IHC 1:50~1:200
Purity
Affinity-chromatography
Modification
Unmodified
Molecular Weight
37kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CRX Antibody detects endogenous levels of total CRX
Applications Notes
Western blot analysis of CRX expression in Y79 cell lysate.
Host or Source
Rabbit
Available Sizes
Curated Selection
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